Panax Ginseng and Fatigue

Ninety men and women with idiopathic chronic fatigue (ICF) were enrolled in a 4 week randomized, double-blind, placebo-controlled trial of ethanoic extract of Panax ginseng to assess ginseng’s efficacy for reduction of fatigue. Significant improvements in fatigue were noted (on mental numeric and visual analog scales) for participants consuming 2 grams of the extract a…

Calcium and Vitamin D for Preeclampsia

49 pregnant women at risk for preeclampsia were supplemented with either 500 mg calcium carbonate and 200 IU (n= 25), or placebo (N=24) and followed for nine weeks. Consumption of the calcium/vitamin D supplement resulted in significant reduction in fasting blood glucose (-9.1 mg dL(-1); p = 0.03) and triglyceride levels (-11.7 mg dL(-1); p…

Folic Acid Supplementation and Cancer Risk

With growing concern over the relationship between folic acid supplementation and cancer risk a meta-analysis was conducted to better elucidate the relationship. The analysis reported no increased risk of total cancer incidence, colorectal cancer, prostate cancer, lung cancer, breast cancer, or hematological malignancy, and a significant reduced risk of melanoma. As reported: Total cancer incidence…

EGCG and inflammation

The authors of this review suggest chronic systemic inflammation as the linkage point between rheumatoid arthritis (RA) and increased cardiovascular dysfunction often associated with RA (see: Solomon DH et al, Circulation. 2003 Mar 11;107(9):1303-7). This review reports on the anti-inflammatory actions of the green tea extract epigallocatechin-3 gallate (EGCG) in multiple studies and suggests its…

Oral Vitamin D and Psoriasis

Topical vitamin D has long been a treatment for psoriasis vulgaris, but a recent review of the literature support oral vitamin D as also efficacious. The literature also suggests a relationship between low serum vitamin D levels and severity of disease, as well as oral vitamin D positively affecting psoriatic arthropathy. J Dermatolog Treat. 2013…

N-acetylcysteine and Psychiatric Disorders

A review of the use of N-acetylcysteine (NAC) in neuropsychiatry suggests that NAC positively affects such diverse disorders as drug addiction, autism, schizophrenia, depression, and bipolar disorder. The authors caution that much of the research is preliminary and requires further study, but that NAC is well tolerated and a potentially novel therapeutic option for people…