Why was this study done? An analytical methodology development for total N-acetyl-L-cyteine (NAC) in multivitamin supplement is necessary for an accurate NAC analysis due to its unstable and easily oxidizing nature. What did the study find? An sensitive and reliable High performance liquid chromatography (HPLC) test method has been developed for that analysis of total…
Why was this study done? Certain selenium compounds have the potential to be harmful and may arise if raw materials for supplements are not chosen wisely. This study was designed to test the toxicity of different selenium compounds. What did the study find? This study found that selenocystine was potentially toxic, but sodium selenite was…
Why was this study done? Ensuring deliverability to nutrients is of utmost importance to supplement manufacture. This study was designed to investigate a method for determining dissolution of vitamin C. What did the study find? This study presented a method for determining the dissolution of a time-release vitamin C product. Pattison T, Allen R, Ashley…
Why was this study done? Selenium is considered an important mineral for health maintenance and possibly for the prevention of certain cancers. There are geographic areas of the world where this mineral is deficient and the necessity of supplementation becomes important. This study was designed to assess differing forms of selenium (sodium selenite versus selenomethionine)…
Why was this study done? Determining the effectiveness of supplemental forms of nutrients is of upmost importance for the manufacture of quality supplements. This study was designed to test the effectiveness of an algae-derived beta-carotene compared to food-based (carrots). What did the study find? This study found that supplemental carotenes (in an oily base derived…
Why was this study done? This study was designed to investigate the assessment of vitamin A status in humans. What did the study find? The study determined that fasting is the best state to determine vitamin A status as many blood changes occur following a carotene-rich meal. Acute Effects of Dietary Carotenes on Serum Alpha…
Why was this study done? Beta-carotene has many health benefits and is a safe method to increase both beta-carotene and vitamin A status. High doses of beta-carotene, though, have been reported to change the coloring of the skin. This study was designed to investigate higher dosing of beta-carotene (30,000 IU, 60,000 IU, 90,000 IU) along…
Why was this study done? It can be difficult to measure the antioxidant ability of various substances. This study was designed to assess the accuracy and reproducibility of an antioxidant measurement system (MatTek EPI-100). What did the study find? The study found that the MatTek EPI-100 was a good assessment tool for determining antioxidant ability…
Why was this paper written? Clinical testing requirements for personal care products (skin cleansers, moisturizers, skin treatment products, shampoos, soaps, etc.) are very different from most other products in the U.S. consumer marketplace. These differences dictate the way in which claim substantiation testing of personal care products is carried out. Since personal care products fall…
Why was this study done? Determining the quality and quantity of active ingredients in raw materials is important for supplement manufacturing. This study was designed to understand the best method of determining Coenzyme Q10 content in raw materials and finished products. What did the study find? The findings of the study suggest that high-performance liquid…