Why was this study done?
Beta-carotene has many health benefits and is a safe method to increase both beta-carotene and vitamin A status. High doses of beta-carotene, though, have been reported to change the coloring of the skin. This study was designed to investigate higher dosing of beta-carotene (30,000 IU, 60,000 IU, 90,000 IU) along with a high beta-carotene diet (for an additional 25,000 – 30,000 IU a day) and its effects on skin color.
What did the study find?
After twelve weeks, no skin changes were seen in the first group (total of around 60,000 IU/day – from diet and supplementation). Seven out of nine participants in the middle group (90,000 IU total a day), and all of the highest group (120,000 IU total) had skin changes. None of the participants in the study had altered blood chemistry during the study.