Why was this study done?

Astronauts commonly experience dehydration during long flights. It is important to understand the role of rehydration formulas and their ability to prevent dehydration (maintenance of plasma volume). This study was designed to better understand the role of differing concentrations of rehydration formulas on dehydrated subjects.

What did the study find?

The rehydration formulas that contained similar sodium concentrations to blood plasma (isotonic concentrations) were the most successful at returning plasma volume to normal levels following dehydration.

Vascular Uptake of Rehydration Fluids in Hypohydrated Men at Rest and Exercise
Authors: Greenleaf JE, et al. NASA Tech Memo, 1992(August):1039-42.
PDF Manuscript: NASA Tech Memo, 1992.