Why was this study done?

Folic acid is a B vitamin that is important for cellular growth and repair. Folic acid is especially important for women of childbearing age, as many birth defects (primarily neural tube defects) can be avoided with proper supplementation. This study was designed to help determine the optimal amount of folic acid supplementation.

What did the study find?

This study found that supplementing with 400 mcg of folic acid did help to return serum folic acid levels in smokers and non-smokers who normally eat a low-folic acid diet.

Improvement in Folate Indices in Blood and Seminal Plasma Following Vitamin Supplementation in Smokers and Nonsmokers.
Authors: Wallock LM, et al. FASEB J, 1999. 13:  A890.
PDF Abstract: FASEB J, 1999.